Interventions for deficits in recognition of emotions in facial expressions in major depressive disorder: An updated systematic review of clinical trials
Authors:
José Augusto Silva Reis, Giordano Novak Rossi, Flávia L Osório, José Carlos Bouso, Jaime Eduardo Cecílio Hallak, and Rafael Guimarães dos Santos.
Journal:
Neuroscience & Biobehavioral Reviews
Year:
2023
About the study
The study focuses on the recognition of emotions in facial expressions (REFE), a key aspect of social cognition, and its alteration in major depressive disorder (MDD). It reviews clinical trials to assess how treatments like antidepressants, psychedelics, and psychotherapy can normalize or reduce REFE biases in MDD patients.
Abstract
The recognition of emotions in facial expressions (REFE) is a core construct of social cognition. In the last decades, studies have showed that REFE is altered in major depressive disorder (MDD), but the evidence is conflicting. Thus, we conducted a systematic review of clinical trials involving therapeutic interventions in MDD and any evaluation of REFE to update (2018–2023) and systematically evaluate the evidence derived from controlled clinical trials on the effects of therapeutic strategies to MDD on the REFE. Eleven studies were included in the final review. Some interventions, including drugs (ketamine, bupropion, psylocibin) and non-pharmacological strategies (psychotherapy) seem to be able to reduce pre-existing REFE biases in MDD patients. However, there was a high heterogeneity in the evaluated studies, in terms of sample, interventions, tasks and results. Further studies and more consistent evaluation tools are highly needed to better understand nuanced deficits and specific actions of different treatment options.
Photo by Ilaria Coradazzi on Flickr.
Categories:
Studies & papers
, Others
Tags:
scientific research
, study
, depression
, social cognition
, emotion processing
, facial expressions